Kolésterol
| Kolésterol | |
|---|---|
 | |
 | |
Jeneng IUPAC (3)-cholest-5-en-3-ol | |
Jeneng liya (10R,13R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | |
| Identifikasi | |
| Nomor CAS | [57-88-5] |
| PubChem | |
| KEGG | D00040 |
| SMILES | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
| InChI | 1/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 |
| Sifat | |
| Rumus molekul | C27H46O |
| Massa molar | 386.65 g/mol |
| Panampilan | white crystalline powder[1] |
| Densitas | 1.052 g/cm3 |
| Titik leleh | 148150 °C[1] |
| Titik umob | 360 °C (decomposes) |
| Kelarutan dalam air | 0.095 mg/L (30 °C) |
| Kelarutan | soluble in acetone, benzene, chloroform, ethanol, ether, hexane, isopropyl myristate, methanol |
| Kejaba ditélakaké suwaliké, data ing ndhuwur kanggo ing suhu lan tekanan standar (25°C, 100 kPa) Sangkalan lan referensi | |
Kolesterol adalah metabolit yang mengandung lemak sterol[2] (Basa Inggris: waxy steroid) yang ditemukan pada membran sel dan disirkulasikan dalam plasma darah.[3] Ya iku sawijing lipid kang awujud molekul lemak utawa kang meh padha. Kolesterol ya iku jinis khusus lipid kang disebut steroid. Steroids ya iku lipid kang nduwèni struktur kimia khusus. Struktur iki asalé saka 4 ali-ali atom karbon.
Steroid liyané kalebu steroid hormon kayata kortisol, estrogen, lan testosteron. Nyatané,kabéh hormon steroid digawé saka owahan-owahan struktur dasar kimia kolesterol. Nalika gawé sawijiné molekul saka ngubahan molekul kang luwih gampang, para ilmuwan nyebut sintesis.
Hiperkolesterolemia tegesé bilih kadar kolesterol luwih dhuwur ing jero getih.
Kolesterol bisa digawé kanthi cara sintetik. Kolesterol sintetik saiki wiwit ditrepké ing teknologi layar lebar (billboard) sebagai alternatif LCD.[4]
Dhuwuré kadar kolestrol ing jero awak dadi pemicu metuné werna penyakit. Pola mangan séhat minangka faktor utama kanggo nyingkiri babagan iku. Ananging, ora kabéh kolestrol duwé dampak buruk kanggo awak. Namung kolestrol kang kalebu kategori LDL waé kang berakibat buruk éwondéné jinis kolestrol HDL minangka kolestrol kang bisa melarutkan kolestrol jahat ing jero awak. Batas normal kolesterol ing jero awak ya iku 160200 mg. Kadar kolesterol kang dhuwur bisa dimudhunké nganggo simvastatin.[5]
Cathetan suku
- ^ a b "Safety (MSDS) data for cholesterol". Retrieved 2007-10-20.
- ^ (en)Michelle A, Hopkins J, McLaughlin CW, Johnson S, Warner MQ, LaHart D, Wright JD. (1993). Human Biology and Health. Englewood Cliffs, New Jersey, USA: Prentice Hall. ISBN 0-13-981176-1. OCLC 32308337.
- ^ (en) Lua error nèng package.lua larik 80: module 'Modul:Citation/CS1/Suggestions' not found.
- ^ Eric Pfanner. A place where cholesterol is welcome: in billboards. The New York Times edition in Süddeutsche Zeitung. Jan. 8, 2007.
- ^ (en)"Factor XIII". Wojewodzki Szpital Zespolony, University of Barcelona Faculty of Medicine, et al; Robert A Schwartz, Elzbieta Klujszo, et al. Retrieved 2010-04-29.. Effects of other agents on FXIII, 4th paragraph
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